Lipid transfer proteins

Plasma lipid transfer proteins

The composition of the plasma lipoproteins is continuously modified during their intravascular metabolism, as a result of a dynamic exchange and net transfer of lipids between particles or between particles and cells. Specialized proteins, the plasma lipid transfer proteins, facilitate the transfer and exchange of phospholipids, cholesteryl esters, and triglycerides between the lipoproteins. Al...

Plasma lipid transfer proteins.

The plasma lipid transfer proteins mediate the transfer and exchange of phospholipids and neutral lipids between the plasma lipoproteins. The cholesteryl ester transfer protein (CETP) and the phospholipid transfer protein (PLTP) are members of the lipid transfer/lipopolysaccharide binding gene family. The CETP contains binding sites for cholesteryl ester and triglycerides and probably acts by a...

Lipid transfer proteins.

Lipid transfer proteins were discovered in our labe ratory as a result of studies that began with the question: How are lipid components of plasma lipoproteins taken up by the liver cell? It soon became apparent that these cells contained a cytosolic factor ( I ) , which transferred PC from one membrane to another. Upon demonstrating that the factor was nondialyzable, heat-labile, and sensitive...

Lipid Transfer Proteins: Moving Molecules?

Lipid-transfer Proteins in Plants.

Lipid-transfer proteins (LTP) are basic, 9-kDa proteins present in high amounts (as much as 4% of the total soluble proteinss) in higher plants. LTPs can enhance the in vitro transfer of phospholipids between membranes and can bind acyl chains. On the basis of these properties, LTPs were thought to participate in membrane biogenesis and regulation of the intracellular fatty acid pools. However,...